Further Message: Is the elixir of longevity for dogs still far from that for humans?

FDA agrees with Loyal's data to support reasonable expectations for the effect of extending the lifespan of large dogs.Research on the longevity of pet dogs and its inspiration for humans!

Loyal has launched the "Dog Anti Aging Program", which is not a government project, but has collaborated with a large number of top academic institutions, such as MIT, Princeton University, and Harvard Medical School. The company has raised tens of thousands of pet dogs, with every move of their owners being recorded, and academic institutions responsible for basic and clinical research; Dogs age 7 times faster than humans, making it a good research model; At present, the definitive factor for dog aging is DNA damage, which triggers signaling pathways to activate the immune system and clear affected cells when accumulated, resulting in tissue damage; Another pathway for DNA destruction is the insertion of ancient viral fragments into the genome, which have evolved for millions of years and cause gene silencing, resulting in epigenetic effects; The "Dog Anti Aging Program" is evaluating three drugs, LOY-001, LOY-002, and LOY-003, to overcome dog aging. The structures of LOY-001 and LOY-003 are unknown, but 002 is similar to the anti-aging drug rapamycin we are currently studying; In short, this is more reliable than research on worms, fruit flies, and mice!

Rapamycin （LOY-002；CAS 53123-88-9）